We present the twenty first report of ART procedures, which includes procedures performed during 2010, by 140 centers in Latin America.
This is the first time data was registered on a case-by-case bases and not as a summary of performed cases as in previous reports.
This new way of register data allowed us to make a deeper analysis of the information given by member centers of REDLARA.
The implementation of this new pattern has demanded a tremendous regional effort due to no previous multinational registry performed on case-by-case bases. Centers reported their ART procedures data electronically and this data was accepted after consistency checks were performed and the institution was certified by an accreditation team.
A total of 37,853 initiated ART cycles included, 3,731 IVF cycles; 22,637 ICSI cycles; 5,157 FET cycles and 6,320 OD embryo transfer, plus 8 cases of GIFT, which are not described in this report.
The majority (39%) of ET in IVF/ICSI cycles were performed in women aged 35-39 years. The delivery rates (DR) per OPU in IVF and ICSI cycles were 30.9%, and 28.8% respectively. The multiple delivery rates in IVF/ICSI cycles were 23.9% (22.1% twins and 1.8% triplets).
When ≥ 2 embryos were transferred, neither the CPR nor the proportion of twins increased significantly. However, the proportion of triplet pregnancies increased significantly when ≥3 embryos were transferred. In OD cycles, twins and triplets deliveries were 25.4% and 2.2% respectively. In FET cycles, twin and triplet deliveries were 17.6% and 1.5% respectively.
Multiple deliveries were associated with a significant increase in preterm delivery and perinatal mortality. The CPR was 18% with eSET and 43% with eDET. In women aged ≤34 years, CPR with eSET was 30% and 52% with eDET. In OD cycles, the CPR with eSET was 29%, and 52% with eDET.
Conclusions: Overall, delivery rates of different ART procedures are comparable to developed countries in the world. However, REDLARA has to enforce the reduction in the number of embryos transferred in IVF/ICSI and OD cycles, in order to prevent multiple births and decrease the corresponding perinatal complications.
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